CAS No.: 519-02-8
苦参碱 Catalog No. CSN19330
Synonyms: 苦参碱;Matridin-15-one;Vegard
(+)-Matrine is a naturally occuring κ-opioid and μ-opioid receptor agonist.
| 规格 | 价格 | 促销价格 | 库存 | 数量 |
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Zhang Y, Zhang H, et al.Effects of matrine against the growth of human lung cancer and hepatoma cells as well as lung cancer cell migration. Cytotechnology. 2009 Apr;59(3):191-200.
- [2] Higashiyama K, Takeuchi Y. et al. Implication of the descending dynorphinergic neuron projecting to the spinal cord in the (+)-matrine- and (+)-allomatrine-induced antinociceptive effects. Biol Pharm Bull. 2005 May;28(5):845-8.
- [3] Wei R, Cao J, Yao S. Matrine promotes liver cancer cell apoptosis by inhibiting mitophagy and PINK1/Parkin pathways. Cell Stress Chaperones. 2018 Nov;23(6):1295-1309
- [4] Tan C, Qian X, Jia R, Wu M, Liang Z. Matrine induction of reactive oxygen species activates p38 leading to caspase-dependent cell apoptosis in non-small cell lung cancer cells. Oncol Rep. 2013 Nov;30(5):2529-35
- [5] Chen L, Chen L, Wan L, Huo Y, Huang J, Li J, Lu J, Xin B, Yang Q, Guo C. Matrine improves skeletal muscle atrophy by inhibiting E3 ubiquitin ligases and activating the Akt/mTOR/FoxO3α signaling pathway in C2C12 myotubes and mice. Oncol Rep. 2019 Aug;42(2):479-494
- [6] Sun K, Yang P, Zhao R, Bai Y, Guo Z. Matrine Attenuates D-Galactose-Induced Aging-Related Behavior in Mice via Inhibition of Cellular Senescence and Oxidative Stress. Oxid Med Cell Longev. 2018 Nov 27;2018:7108604
- [7] Gu YY, Chen MH, May BH, Liao XZ, Liu JH, Tao LT, Man-Yuen Sze D, Zhang AL, Mo SL. Matrine induces apoptosis in multiple colorectal cancer cell lines in vitro and inhibits tumour growth with minimum side effects in vivo via Bcl-2 and caspase-3. Phytomedicine. 2018 Dec 1;51:214-225
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 519-02-8 | 储存条件 |
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| 分子式 | C15H24N2O | 运输 | 蓝冰 | |||||||
| 分子量 | 248.36 | 别名 | 苦参碱;Matridin-15-one;Vegard;α-Matrine | |||||||
| 溶解度 |
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动物实验配方 |
